An Overview of Feldene – Active Ingredient Piroxicam and Mechanism of Action as a Nonsteroidal Anti-Inflammatory Drug (NSAID)


Active ingredient: Piroxicam

Dosage: 10mg, 20mg

$0,46 per pill

Short Introduction to Feldene

Feldene is a widely used medication that belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). It contains the active ingredient piroxicam, which is known for its potent anti-inflammatory and analgesic properties.

Active Ingredient: Piroxicam

Piroxicam is a nonsteroidal anti-inflammatory drug that works by inhibiting the production of prostaglandins, substances in the body that cause inflammation, swelling, and pain. It is a member of the class known as oxicams, which are among the most effective NSAIDs available.

Mechanism of Action

Feldene acts by selectively blocking the enzyme cyclooxygenase (COX), which is responsible for the synthesis of prostaglandins. By inhibiting COX, Feldene reduces the production of prostaglandins and ultimately reduces inflammation and pain.

Feldene is available in various forms, including oral capsules and suppositories. It is commonly prescribed for the treatment of various conditions, including osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

Feldene: Key Features

  • Active ingredient: Piroxicam
  • Class: Nonsteroidal anti-inflammatory drug (NSAID)
  • Mechanism of action: Inhibition of the cyclooxygenase enzyme and subsequent reduction of prostaglandin production
  • Forms: Oral capsules and suppositories
  • Indications: Osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis

Why Feldene Is Effective

Feldene’s effectiveness lies in its ability to target the root cause of inflammation and pain, rather than merely masking the symptoms. By specifically inhibiting the cyclooxygenase enzyme, it directly interferes with the production of pro-inflammatory substances, providing long-lasting relief.

Patients who use Feldene often experience a significant reduction in joint stiffness, swelling, and associated discomfort. Its unique mechanism of action sets it apart from other pain relievers, making it a preferred choice for individuals seeking effective and targeted pain management.

If you require more detailed information about Feldene, please consult reputable sources such as the official FDA prescribing information or consult with a healthcare professional.

Remember, it’s essential to seek professional advice before starting any new medication to ensure it’s suitable for your specific needs and medical condition.

Overview of Feldene – Piroxicam as an Active Ingredient

Feldene is a widely used medication that belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). The key component of Feldene is piroxicam, which is the active ingredient responsible for the therapeutic effects of the drug. Piroxicam is a potent NSAID that provides pain relief, reduces inflammation, and lowers fever.

Mechanism of Action as an NSAID

Feldene works by inhibiting the production of certain enzymes called cyclooxygenases (COX), specifically COX-1 and COX-2. These enzymes play a crucial role in the synthesis of prostaglandins, which are responsible for pain, inflammation, and fever. By blocking the action of COX enzymes, Feldene effectively reduces the production of prostaglandins, leading to pain relief and reduced inflammation.

Benefits of Feldene as an NSAID:

  • Effective pain relief
  • Reduces inflammation
  • Controls fever
  • Improves overall well-being

According to the National Institute of Health (NIH), NSAIDs like Feldene are widely used to manage various conditions such as arthritis, menstrual cramps, sprains, strains, and other musculoskeletal injuries.

Important Usage Information:

Drug Name: Feldene
Active Ingredient: Piroxicam
Dosage Forms: Tablets, capsules, or gel
Administration: Oral and topical
Recommended Dosage: As prescribed by the healthcare professional
Possible Side Effects: Stomach upset, indigestion, dizziness, headache

It is crucial to follow the dosage instructions provided by your healthcare professional or as mentioned on the medication label. Taking more than the prescribed dosage may lead to adverse effects.

Cautions and Warnings:

  • Avoid using Feldene if you have a known allergy to piroxicam or any other NSAIDs.
  • Prior consultation with a healthcare professional is necessary if you have a history of stomach ulcers, bleeding disorders, heart problems, or kidney disease.
  • Do not consume alcohol while taking Feldene, as it may increase the risk of stomach bleeding.
  • Inform your healthcare professional about any other medications, supplements, or herbal products you are currently using to minimize the risk of drug interactions.

For more information on the usage, dosage, and potential side effects of Feldene, refer to the official prescribing information available at the FDA’s database.

By understanding the mechanism of action and benefits of Feldene as an NSAID, individuals can make informed decisions regarding its usage under the guidance of healthcare professionals.

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Active ingredient: Piroxicam

Dosage: 10mg, 20mg

$0,46 per pill

The Mechanism of Action of Feldene

Feldene is a nonsteroidal anti-inflammatory drug (NSAID) that contains the active ingredient Piroxicam. This drug is widely used for its ability to alleviate pain, inflammation, and swelling caused by various medical conditions.
How Does Feldene Work?
The mechanism of action of Feldene involves its inhibitory effect on specific enzymes known as cyclooxygenases (COX). COX enzymes play a crucial role in the production of prostaglandins, which are chemical messengers responsible for inflammation and pain in the body.
By inhibiting the COX enzymes, Feldene reduces the production of prostaglandins, thereby decreasing inflammation and relieving pain. Additionally, this drug may also help reduce fever by affecting the hypothalamic heat-regulating center in the brain.
Specific Effects of Feldene:
Feldene exerts its effects through the following mechanisms:

  1. Anti-inflammatory effect: By decreasing prostaglandin production, Feldene inhibits the inflammatory response, providing relief from pain, redness, and swelling associated with conditions such as arthritis, bursitis, and tendonitis.
  2. Pain relief: The inhibition of prostaglandin production by Feldene helps to lower pain sensitivity and reduce discomfort caused by injuries, surgeries, or chronic conditions.
  3. Fever reduction: Feldene’s impact on the hypothalamic heat-regulating center lets it lower elevated body temperatures resulting from fevers associated with infections or other illnesses.
  4. Improved joint function: Feldene’s anti-inflammatory and analgesic properties assist in reducing joint stiffness, improving mobility, and enhancing overall joint function in individuals suffering from conditions like rheumatoid arthritis and osteoarthritis.
  5. Prevention of blood clot formation: Feldene’s inhibition of COX enzymes also affects platelet aggregation, which may provide some protection against the formation of blood clots in certain individuals.

Important Considerations:
While Feldene offers therapeutic benefits, it is essential to remember that it is a prescription medication, and its usage should strictly follow the guidance of a healthcare professional.
Moreover, Feldene is associated with potential side effects, including gastrointestinal distress, cardiovascular risks, and allergic reactions. Therefore, it is crucial for patients to be aware of these risks and consult their healthcare provider if they have any concerns.
Feldene, containing the active ingredient Piroxicam, is an NSAID that exerts its effects by inhibiting the production of prostaglandins, thereby reducing inflammation and providing pain relief. With its broad range of therapeutic applications, Feldene proves to be a valuable medication for individuals suffering from conditions involving inflammation and pain.
For further information on Feldene and its usage, it is recommended to visit reputable sources such as the National Institutes of Health (NIH) or consult with a healthcare professional.

Use of Feldene

Feldene, a nonsteroidal anti-inflammatory drug (NSAID), is commonly used for the treatment of various conditions due to its active ingredient, Piroxicam. Below are some of the specific uses of Feldene:

Rheumatoid Arthritis and Osteoarthritis

Feldene is prescribed to manage the symptoms and reduce inflammation associated with rheumatoid arthritis and osteoarthritis. These are chronic conditions that affect the joints, causing pain, stiffness, and swelling. By inhibiting the production of certain chemicals in the body that cause inflammation, Piroxicam helps alleviate the symptoms, allowing individuals with arthritis to experience improved joint flexibility and reduced pain.

Acute Pain

In cases where individuals experience acute pain, such as from dental procedures, surgeries, or injuries, Feldene may be prescribed to provide relief. By blocking the production of prostaglandins, substances responsible for sensitizing nerve endings and triggering pain and inflammation, Feldene helps alleviate acute pain and discomfort.


Dysmenorrhea, commonly known as menstrual cramps, refers to the intense pain experienced by some women during their menstrual period. Feldene can be prescribed to relieve the pain and reduce the severity of menstrual cramps. By suppressing the production of prostaglandins, which contribute to uterine contractions and inflammation, Feldene helps alleviate the pain associated with dysmenorrhea.

Ankylosing Spondylitis

Ankylosing spondylitis is a chronic inflammatory disease that primarily affects the spine, causing pain, stiffness, and limited mobility. Feldene can be prescribed to manage the symptoms associated with ankylosing spondylitis, including reducing inflammation and improving joint flexibility. By inhibiting prostaglandin synthesis, Piroxicam helps alleviate the pain and discomfort associated with this condition.

Other Conditions

Additionally, Feldene may be used in the treatment of other conditions, as determined by a healthcare professional. It is important to follow the prescribed dosage and instructions provided by the healthcare professional to ensure safe and effective use of the medication.

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For more information on the uses of Feldene and its potential side effects, it is recommended to refer to reputable sources such as the National Center for Biotechnology Information (NCBI) or consult with a healthcare professional.

Feldene: The Nonsteroidal Anti-Inflammatory Drug for Effective Pain Relief

If you are seeking a powerful treatment for pain and inflammation, Feldene is the drug you need. With its active ingredient Piroxicam, this nonsteroidal anti-inflammatory drug (NSAID) offers outstanding relief while significantly reducing the discomfort caused by various conditions. Let’s dive deeper into how Feldene works and why it is a popular choice among healthcare professionals.

Feldene’s Active Ingredient: Piroxicam

One of the key components of Feldene is Piroxicam. Backed by extensive research, Piroxicam has proven to be highly effective in managing pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and menstrual pain.
Piroxicam belongs to the class of NSAIDs, which are widely used for their potent anti-inflammatory properties. These drugs inhibit the production of prostaglandins, chemicals in the body that contribute to inflammation and pain.

Feldene’s Mechanism of Action

Feldene works by blocking the enzymes responsible for producing prostaglandins. By reducing the levels of these inflammatory chemicals, Feldene helps alleviate pain and inflammation, enabling individuals to carry out their daily activities without hindrance.
Moreover, Feldene’s mechanism of action doesn’t only target pain relief. It also addresses swelling, stiffness, and joint tenderness associated with arthritis and other inflammatory conditions.

The Benefits of Choosing Feldene

When it comes to managing pain, Feldene stands out from other NSAIDs. Here are some of its benefits:

  • Potent pain relief: Feldene provides powerful pain relief, allowing individuals to experience immediate comfort and enhanced quality of life.
  • Long-lasting effects: With its extended half-life, Feldene ensures that pain relief lasts for an extended period, reducing the need for frequent dosing.
  • Effective anti-inflammatory properties: Feldene’s ability to reduce inflammation makes it an ideal choice for individuals suffering from conditions such as arthritis.
  • Diverse applications: Besides arthritis, Feldene is also prescribed for other conditions like ankylosing spondylitis and menstrual pain.

Seek Expert Advice

While Feldene offers significant benefits, it is crucial to consult a healthcare professional before starting any medication. Your doctor will determine the appropriate dosage and duration of treatment based on your specific condition and medical history.
For more detailed information about Feldene and its proper usage, visit the official website of the Feldene manufacturer or refer to reliable sources such as the National Center for Biotechnology Information or the Mayo Clinic.
Remember, effectively managing pain and inflammation can significantly improve your quality of life, and Feldene is here to lend you a helping hand.


Active ingredient: Piroxicam

Dosage: 10mg, 20mg

$0,46 per pill

Feldene: A Comprehensive Overview

In this article, we will delve into the details of Feldene, a widely used nonsteroidal anti-inflammatory drug (NSAID). We will explore its active ingredient, Piroxicam, and understand the mechanism of action through which it provides relief from inflammation and pain.

Active Ingredient: Piroxicam

Piroxicam is the key component of Feldene and belongs to the class of NSAIDs. It is renowned for its potent analgesic and anti-inflammatory properties. As a non-selective inhibitor of cyclooxygenase (COX), Piroxicam impedes the production of prostaglandins, which are responsible for inflammation, pain, and fever.

Understanding Feldene’s Mechanism of Action

As an NSAID, Feldene exerts its therapeutic effects through multiple mechanisms:

  1. Inhibition of Prostaglandin Synthesis: Piroxicam inhibits the activity of COX enzymes, namely COX-1 and COX-2. By blocking these enzymes, it diminishes the synthesis of inflammatory mediators called prostaglandins. With reduced levels of prostaglandins, inflammation and pain signals are suppressed.
  2. Anti-inflammatory Activity: By mitigating prostaglandin levels, Feldene exhibits remarkable anti-inflammatory properties. This is especially beneficial for conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis, where excessive inflammation causes discomfort and joint damage.
  3. Analgesic Effects: Through its impact on prostaglandin synthesis, Feldene effectively relieves pain. Whether it is a mild headache, menstrual cramps, or chronic pain associated with arthritis, Piroxicam provides respite by acting on the central nervous system.
  4. Fever Reduction: Elevated levels of prostaglandins in the brain can lead to a rise in body temperature, resulting in fever. Feldene’s ability to suppress prostaglandin production helps in reducing fever and alleviating associated symptoms.
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Apart from its primary mechanisms of action, Feldene may also exert additional effects, including platelet aggregation inhibition, improved blood flow, and cartilage preservation. These secondary effects contribute to the overall therapeutic benefits offered by the drug.

Considering the potential side effects and interactions associated with Feldene, it is crucial to seek professional medical advice before initiating its use. Your healthcare provider can determine the appropriate dosage and duration of treatment based on your specific condition and medical history.

To learn more about Feldene and its usage, we recommend visiting the following authoritative sources:

By gaining a thorough understanding of Feldene and its therapeutic properties, individuals can make informed decisions regarding its usage and potential benefits in managing their specific health conditions.

7. Potential Side Effects and Precautions

Feldene, like any other medication, may cause side effects in some individuals. It is important to be aware of these possible side effects and take necessary precautions while using the drug. Below is a list of potential side effects associated with the use of Feldene:

  1. Gastrointestinal Effects: Feldene may cause stomach pain, nausea, indigestion, diarrhea, or constipation. In some cases, it may also lead to peptic ulcers, gastrointestinal bleeding, or perforation. It is advisable to take the medication with food to reduce the risk of gastrointestinal issues.
  2. Cardiovascular Effects: Piroxicam, the active ingredient in Feldene, has been associated with an increased risk of heart attack or stroke, particularly when used for long-term or at high doses. Individuals with existing cardiovascular conditions should exercise caution while using Feldene and consult their healthcare provider for a thorough evaluation of the risks and benefits.
  3. Renal Effects: Feldene can affect kidney function and may lead to fluid retention, edema, or worsening of pre-existing kidney conditions. Individuals with kidney problems should inform their healthcare provider before starting the medication.
  4. Allergic Reactions: Some people may be hypersensitive to Feldene and may experience allergic reactions such as rash, itching, swelling, or difficulty breathing. If any allergic symptoms occur, immediate medical attention should be sought.
  5. Central Nervous System Effects: Feldene may rarely cause dizziness, headache, drowsiness, or blurred vision. It is recommended to avoid activities that require mental alertness until the individual knows how the drug affects them.
  6. Other Potential Side Effects: Additional side effects that have been reported with Feldene include liver abnormalities, blood disorders, skin disorders, and visual disturbances. It is important to inform healthcare providers of any unusual symptoms experienced while using the medication.

While the list above covers most potential side effects, it is not exhaustive. Individuals should carefully read the medication’s package insert and consult their healthcare provider for a comprehensive understanding of the risks and precautions associated with Feldene.

It is crucial to follow the prescribed dosage and duration of treatment as advised by the healthcare provider. Abrupt discontinuation or misuse of Feldene may lead to adverse effects. Regular check-ups and monitoring of the individual’s condition are also necessary to assess the drug’s efficacy and identify any potential side effects.

If any side effects or concerns arise while using Feldene, individuals should promptly contact their healthcare provider for further guidance. Open communication with healthcare professionals is key to ensuring the safe and effective use of the medication.

For more detailed information on Feldene, its side effects, and precautions, please refer to the authoritative sources below:

Remember, the information provided in this article is solely for educational purposes and should not replace professional medical advice. Consult a healthcare professional for personalized guidance regarding your specific condition and treatment options.